KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFFL
All Species:
14.24
Human Site:
S168
Identified Species:
44.76
UniProt:
Q8WZ73
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WZ73
NP_001017368.1
363
40514
S168
F
L
T
Q
P
H
S
S
M
V
P
P
T
S
P
Chimpanzee
Pan troglodytes
Q95M72
236
27118
G44
V
Q
C
F
H
C
G
G
G
L
A
N
W
K
P
Rhesus Macaque
Macaca mulatta
XP_001111649
358
39920
L162
F
P
E
Q
Q
A
F
L
T
Q
P
H
S
S
M
Dog
Lupus familis
XP_853784
363
40172
S168
F
L
T
Q
P
H
A
S
T
V
P
P
T
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQM0
377
42230
S182
F
L
T
Q
P
Q
T
S
T
V
P
P
T
S
P
Rat
Rattus norvegicus
Q8CIN9
362
40390
S168
F
L
T
Q
P
Q
S
S
T
V
P
P
T
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510920
359
39885
S166
S
S
R
S
Q
T
S
S
F
F
T
H
P
F
F
Chicken
Gallus gallus
Q90660
611
68991
S408
L
I
K
Q
T
V
Q
S
K
I
L
A
T
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.1
95.8
92.5
N.A.
86.2
90.3
N.A.
46
20.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
36.9
97.2
94.4
N.A.
88.3
92.2
N.A.
59.5
34
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
26.6
86.6
N.A.
80
86.6
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
33.3
93.3
N.A.
86.6
86.6
N.A.
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
13
0
0
0
13
13
0
0
0
% A
% Cys:
0
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
13
0
0
0
0
0
0
0
0
0
0
13
13
% E
% Phe:
63
0
0
13
0
0
13
0
13
13
0
0
0
13
13
% F
% Gly:
0
0
0
0
0
0
13
13
13
0
0
0
0
0
0
% G
% His:
0
0
0
0
13
25
0
0
0
0
0
25
0
0
0
% H
% Ile:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
13
0
0
0
0
13
0
% K
% Leu:
13
50
0
0
0
0
0
13
0
13
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
13
0
0
50
0
0
0
0
0
63
50
13
0
63
% P
% Gln:
0
13
0
75
25
25
13
0
0
13
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
13
0
13
0
0
38
75
0
0
0
0
13
63
0
% S
% Thr:
0
0
50
0
13
13
13
0
50
0
13
0
63
0
0
% T
% Val:
13
0
0
0
0
13
0
0
0
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _